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Reference Laboratories

Below is a list of reference laboratories to which work is routinely referred.

Reference Laboratory

Test

Immunology Dept.

Blood Sciences

Pathology Department

Sandwell and West Birmingham Hospital NHS Trust

Sandwell Hospital

Lyndon

West Bromwich

B17 4HJ

Tel: 0121 507 4258

 

Specific antibodies: Haemophilus influenzae b immunity, Streptococcus pneumoniae immunity and Tetanus immunity

PHE,
Birmingham Heartlands Hospital,
Bordesley Green East,
Birmingham B9 5SS

Tel: 0121 424 2500 Switchboard

0121 424 3111- Laboratory Enquiries

 

 

Adenovirus PCR, Coxsackie A & B Virus, CMV PCR, CMV serology, Cryptococcal antigen, Electron Microscopy for Viruses, Enterovirus PCR, Hepatitis A IgG (immunity), HBsAg confirmation,  Hepatitis B markers (HBeAg) and HBeAb), Hepatitis B DNA (HBV Viral load), Hepatitis C antibody, PCR & viral load, Herpes simplex PCR, HIV confirmation,  Legionella  antibody,  Mumps PCR, Mycobacteria culture and sensitivity, Rhinovirus, Respiratory Syncytial Virus (RSV), VZV  IgM/PCR on CSF, E.coli 0157 (confirmation of isolate only), Pneumocystis PCP, MERS Coronavirus

Antimicrobial Reference Laboratory
Microbiology
North Bristol NHS Trust
Southmead Hospital
Bristol
BS10 5NB

Tel: 0117 323 5654/98

 

Antimicrobial Assay Service

Itraconazole, Amikacin, Rifampicin, Streptomycin, Rifambutin levels

Mycology Reference Laboratory
SouthWest PHE Laboratory,

Myrtle Road,
Kingsdown,
Bristol BS2 8EL
 

Tel: 01173425028

 

Identification service for yeasts and moulds, including dermatophytes. Reference antifungal susceptibility testing. Serology for dimorphic pathogens and other unusual infections. National Collection of Fungi.

Voriconazole levels

Aspergillus antigen test (?infection)

Anaerobe Reference Laboratory
NPHS Microbiology Cardiff
University Hospital of Wales
Heath Park
Cardiff CF14 4XW

 

Tel: 029 20 742 171

 

Anaerobes (particularly Clostridium difficile), Actinomyces spp, metronidazole resistance in anaerobes

Liverpool Clinical Laboratories

Virology Department

8th floor Duncan Building

Royal Liverpool and Broad Green University Hospitals NHS Trust

Prescot Street

L7 8XP

Tel: 0151 529 4900

Brucella serology.

Laboratories at PHE:

Centre for Infections

61 Colindale Avenue

London NW9 5EQ

See  Individual laboratories below or refer to web site (www.PHE.org.uk/SRMTests)  for most up to date information on tests and forms:

AMRHAI Reference Unit

Antimicrobial Resistance & Healthcare Associated Infections

Tel 020 8327 6511/7887

 

Exceptional aspects of antimicrobial resistance
S.aureus vanc, teic,lin, tig. CNS vanc, lin tig. HIN 3rd generation carbapenem. Acinetobacter, colistin Coryne jeikeum, vanc, teic lin SPN mero vanc teic lin tige pen>4mg/l cefotaxime >2mg/l  Ps aeruginosa colistin MBL +ve. BHS A,B,C,G pen vanc teic lin tige Enterococci lin teic  Enterobacteriacae ery mero imi colistin

 

Virus reference Department (VRD)

IDU

Immunisation and diagnosis Unit

Tel: 020 8327 6017

 

Measles IgM, Polyoma virus (JC and BK), Polio, Coxsackie,

Virus reference Department ( VRD)

 

SSU

Seromolecular services unit

Tel 0203827 6971

 

HIV-1, HIV-2, Hepatitis D, HBsAg quantitation

GBRU

Gastrointestinal Bacteria Reference Unit

Tel: 020 8327 7887

 

 

Salmonella, Shigella, Vibrio, Yersinia, Campylobacter, Citrobacter, E.coli verotoxin (stool sample only)

Bacillus, Clostridium perfringens, Clostridium botulilum, Listeria, Stahylococcal  toxins.

AMRHAI

Antimicrobial Resistance and Healthcare associated Infections

 

Tel 020 8327 6511/7887

 

Staphylococci, MRSA, Enterococci, Klebsiella, Enterobacter, Serratia, Pseudomonas, Stenotrophomonas, Burkholderia, Acinetobacter, Achromobacter xylosoxidans Hospital Infection Advice

RVPBRU

Respiratory and Vaccine Preventable Bacteria Reference Unit

 

Tel: 0208327 7887

 

Streptococci (Groups A, B, C and G and all other streptococcal species, related genera), Streptococcus pneumoniae, potentially toxigenic corynebacteria (Corynebacterium diphtheriae, C. ulcerans, C. pseudotuberculosis), Diphtheria serology, Bartonella Spp. (cat scratch fever), Haemophilus influenzae, Bordetella spp, Legionella urine Ag confirmation

Virus reference Department (VRD)

AVU

Antiviral Unit

 

Tel: 020 8327 6017

 

HTLV I and II, human papilloma virus, TSEs, Hepatitis D

STBRU

Sexually Transmitted Bacteria Reference Unit

Tel: 020 8327 7887

 

Bacterial sexually transmitted pathogens: Neisseria gonorrhoeae, Treponema palladium, Chlamydia trachomatis

PHE Parasitology Reference Laboratory

Department of Clinical Parasitology
Hospital for Tropical Diseases
Mortimer Market
Capper Street
London
WC1E 6AU

 

Tel: 020 7387 4411

 

Parasites and amoeba

-Taenia serology

-Microsporidium  (faeces)

- Amoebic/hydatid serology

-Filariasis serology

-Toxocara antibodies

PHE Malaria Reference Laboratory
London School of Hygiene and Tropical Medicine
Keppel Street
London
WC1E 7HT

Tel: 020 7636 8636

 

Malaria parasites (Plasmodium spp) Refer all requests to Haematology Dept.

Meningococcal Reference Unit
Clinical Science Building
Manchester Royal Infirmary
Oxford Road
Manchester
M13 9WL

Tel: 0161 276 6757

 

Meningococcal  typing

Meningococcal PCR

Pneumococcal PCR

Microbiology Services

Lancashire Teaching Hospital
Royal Preston Hospital
PO Box 202
Sharoe Green Lane
Fulwood
Preston
PR2 9HT

Tel: 01772 522117

 

Mumps IgM

Measles IgM 

 

Specialist Microbiology Services

Rare and Imported Pathogens

PHE

Porton Down

Salisbury

Wiltshire

SP4 0JG

Tel: + 44 (0) 1980 612 348 (9-5)
Tel: + 44 (0) 1980 612100 (24 hour)

 

Arboviruses, Haemorrhagic Fever Viruses, Nipah and Hendra viruses, Rickettsiae and Coxiella burneti (Q Fever), Bacillus anthracis, Hantavirus, Lyme’s disease (Borrelia) Rabies, Pox viruses including small pox, Lyme disease.

Cryptosporidium Reference Unit
Public Health Wales
Singleton Hospital
Sketty
Swansea
SA2 8QA

Tel : 01792 285341

Cryptosporidia (faeces)

Immunology Department and Protein Reference laboratory

PO BOX 894

Sheffield

S5 7YT

Tel : 0114 271 5552

Aspergillus precipitins
Avian precipitins

 

 

 

Microbiology

The Royal Wolverhampton Hospital NHS Trust
New Cross Hospital
Wednesfield Road
Wolverhamptom
WV3 9QR

Tel : 01902 307999

Speed dial *3147

Mycobacteria culture (all specimens except blood and bone marrow which are sent direct to Heartlands)

PHE Bristol
Myrtle Road
Bristol
BS2 8EL 

Tel: 0117 342 5551

Atypical pneumonia screens

 

Lab 21 Ltd

184 Cambridge Science Park
Milton Road
Cambridge
CB4 0GA

Tel : 01223 395450

 

HIV Therapeutic Drug Monitoring (TDM)

 

Leeds Teaching Hospitals NHS Trust
Old Medical School
Leeds General Infirmary
Leeds
LS1 3EX

Tel: 0113-3928766

Histoplasma serology

National Creutzfeldt-Jakob Disease Surveillance unit

Western General Hospital

Crewe Road

Edinburgh

EH4 2XU

Tel: 0131 537 2128/1980

PrP CJD

CSF maybe stored ready for collection at -70°C. Request/transport all done by clinician. Only lab involvement is storage of specimen prior to transport.

Last Modified by Sital Patel on Oct 31, 2017